Association of Apixaban Therapy and Prothrombin Time in Patients With Atrial Fibrillation–Single Center Cohort Study–

M Kanemoto, H Kuhara, T Ueda, T Shinohara… - Circulation …, 2014 - jstage.jst.go.jp
Background: This study evaluated whether measuring prothrombin time (PT) using particular
reagents of interest predicted apixaban-associated anticoagulant activity in Japanese
patients with non-valvular atrial fibrillation (NVAF). Methods and Results: Two reagents,
Shinplastin Excel S and Coagpia PT-N, were used to evaluate PT under apixaban therapy.
From June 2013 to February 2014, 103 NVAF patients were recruited, and PT was
measured at 3 time points:(1) anytime in the outpatient clinic,(2) at peak, and (3) at trough. In …

Association of Apixaban Therapy and Prothrombin Time in Patients With Atrial Fibrillation: Single Center Cohort Study

K Masashi, K Hiroko, U Toru, S Takahiro, O Takamasa… - 日本循環器學誌, 2014 - cir.nii.ac.jp
Background: This study evaluated whether measuring prothrombin time (PT) using particular
reagents of interest predicted apixaban-associated anticoagulant activity in Japanese
patients with non-valvular atrial fibrillation (NVAF). Methods and Results: Two reagents,
Shinplastin Excel S and Coagpia PT-N, were used to evaluate PT under apixaban therapy.
From June 2013 to February 2014, 103 NVAF patients were recruited, and PT was
measured at 3 time points:(1) anytime in the outpatient clinic,(2) at peak, and (3) at trough. In …
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